The New York Giants ruled wide receiver Odell Beckham Jr. inactive for their Week 1 game against the Dallas Cowboys on Sunday.
Beckham was ruled questionable and a game-time decision earlier in the week after dealing with a sprained ankle suffered in New York's second preseason game.
Though the 24-year-old Beckham told SNY's Taylor Rooks on Friday that he had been feeling a lot better, the Giants will enter the regular season without their leading receiver.
While head coach Ben McAdoo said Beckham was getting treatment throughout the week and was "doing everything he can to get himself well."
Prior to the game, Beckham was warming up on the field for approximately 30 minutes, running routes, stretching and was also seen working with strength coach Aaron Wellman. Among the routes Beckham ran included a 10-yard hook route from Eli Manning and a fade in the end zone.
The Giants also listed linebacker Keenan Robinson out with a concussion. Tight end Matt LaCosse, running back Wayne Gallman, offensive lineman D.J. Fluker, wide receiver Tavarres King and quarterback Davis Webb are also inactive.
Beckham suffered the injury when he took a low hit from Cleveland Browns cornerback Briean Boddy-Calhoun on Aug. 21. Beckham did not play in either of the Giants' final two preseason games and began doing on-field work at practice on Aug. 31.
He was a non-participant at practice this week. While the Giants did not practice on Friday, their injury report said, "Beckham would not have been able to practice today anyway."
Beckham hasn't missed a game due to injury since he missed the first four games of his rookie season in 2014. In three years since the Giants drafted him 12th overall, Beckham has totaled 288 catches for 4,122 yards and 35 touchdowns in 43 games.